Beautiful Plants For Your Interior
Maitake (Grifola frondosa)
Grifola frondosa
The "Dancing Mushroom" of Japan — Maitake (Grifola frondosa) is a large, feathery mushroom prized
in both culinary and medicinal traditions. Rich in D-fraction beta-glucans — among the most potent immune-activating polysaccharides studied — Maitake supports immune function, metabolic health, and
blood sugar balance.
What Is It?
Grifola frondosa — known as Maitake in Japanese (meaning "dancing mushroom," reportedly because people danced with joy upon finding it in the wild) — is a large polypore mushroom that grows at the base of oak, elm, and maple trees across Asia, Europe, and North America.
Highly prized both as a gourmet culinary mushroom and a potent medicinal fungus, Maitake contains a particularly active form of beta-glucan called the D-fraction — one of the most studied immune-modulating polysaccharides from any natural source.
Highly prized both as a gourmet culinary mushroom and a potent medicinal fungus, Maitake contains a particularly active form of beta-glucan called the D-fraction — one of the most studied immune-modulating polysaccharides from any natural source.
How It Works
Maitake's primary bioactive compound — the D-fraction beta-glucan — works through:
- Macrophage and NK Cell Activation — D-fraction binds to receptors on immune cells, strongly activating macrophage phagocytic activity and natural killer cell cytotoxicity
- Dendritic Cell Maturation — supports the development of dendritic cells that coordinate adaptive
immune responses
- Blood Sugar Regulation — Maitake alpha-glucan has demonstrated ability to improve insulin sensitivity
and regulate post-meal blood glucose levels
- Lipid Metabolism — may support healthy cholesterol levels through effects on fatty acid metabolism
- Macrophage and NK Cell Activation — D-fraction binds to receptors on immune cells, strongly activating macrophage phagocytic activity and natural killer cell cytotoxicity
- Dendritic Cell Maturation — supports the development of dendritic cells that coordinate adaptive
immune responses
- Blood Sugar Regulation — Maitake alpha-glucan has demonstrated ability to improve insulin sensitivity
and regulate post-meal blood glucose levels
- Lipid Metabolism — may support healthy cholesterol levels through effects on fatty acid metabolism
Side Effects & Considerations
Maitake is very safe as both a food and supplement:
- Excellent tolerability — long history of culinary and medicinal use
- May lower blood sugar — monitor carefully if on diabetes medications
- May lower blood pressure — monitor if on antihypertensive medications
- Those with autoimmune conditions should consult a doctor due to immune stimulating properties
- Not recommended during pregnancy without medical supervision
- Excellent tolerability — long history of culinary and medicinal use
- May lower blood sugar — monitor carefully if on diabetes medications
- May lower blood pressure — monitor if on antihypertensive medications
- Those with autoimmune conditions should consult a doctor due to immune stimulating properties
- Not recommended during pregnancy without medical supervision
Typical Dosage Range
500mg – 3,000mg daily
Studies use 500-3,000mg of Maitake extract daily.
Safe for consistent daily long-term use.
Within the Troomy Daily 14-mushroom blend, Maitake contributes D-fraction immune activity and
metabolic support.
Research Notes
- Kodama et al. (2002) — Published in the Journal of Alternative and Complementary Medicine,
demonstrated Maitake D-fraction significantly enhanced immune cell activity in cancer patients.
- Kubo & Nanba (1996) — Research in Annals of the New York Academy of Sciences documented
Maitake D-fraction's potent macrophage and NK cell activation.
- Chen et al. (2010) — Study found Maitake extract significantly improved insulin sensitivity and reduced blood glucose levels in postmenopausal women with insulin resistance.
demonstrated Maitake D-fraction significantly enhanced immune cell activity in cancer patients.
- Kubo & Nanba (1996) — Research in Annals of the New York Academy of Sciences documented
Maitake D-fraction's potent macrophage and NK cell activation.
- Chen et al. (2010) — Study found Maitake extract significantly improved insulin sensitivity and reduced blood glucose levels in postmenopausal women with insulin resistance.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

